Hepcidin and beta-thalassemia major – diagnostic and therapeutic aspects
نویسندگان
چکیده
منابع مشابه
Ocular Lymphoma: Clinical, Diagnostic, and Therapeutic Aspects
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متن کاملTransfusion Related Adverse Effects on Beta-Thalassemia Major and New Therapeutic Approaches: A Review Study
Thalassemia is one of the most common genetic disorders, worldwide.Beta-Thalassemia Major (BTM) is the most severe type, which reduces lifeexpectancy and quality of life. In this study, we searched the related keywords to subject from 1996-2019 in the Medline and Web of Science databases, therefore found 250 articles. Moreover, we categorized them into the studies on blood transfusions in...
متن کاملHepcidin levels and iron status in beta-thalassemia major patients with hepatitis C virus infection.
Beta-thalassemia is an inherited anemia in which synthesis of the hemoglobin beta-chain is decreased. Clinical features of beta-thalassemia include variably severe anemia and iron overload due to increased intestinal iron absorption, which may result in damage to vital organs. The hepatic peptide; hepcidin is a key regulator of iron metabolism in mammals. The present study aimed to determine th...
متن کاملPrevalence of HCVAb and HBsAg in Patients with Beta-thalassemia Major in Amirkola Thalassemia Center
Background and purpose: Beta-thalassemia major is a genetic disorder with known globin defect that leads to chronic hemolytic anemia. Due to the need for recurrent blood transfusion, the risk of infectious diseases such as hepatitis is higher in these patients. Materials and methods: This cross-sectional study recruited 518 patients with thalassemia major in Amirkola Thalassemia Center, 2013-2...
متن کاملEndocrine Disorders in Beta thalassemia Major Patients
Background Thalassemia is the most common hereditary disorder worldwide. The patient's’ survival is dependent on lifetime blood transfusion which leads to iron overload and its toxicity on various organs including endocrine glands. The study aimed to investigate endocrine disorders in patients with Beta-thalassemia major in the Southern Khorasan province, Iran. Materials and Methods In this des...
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ژورنال
عنوان ژورنال: Varna Medical Forum
سال: 2020
ISSN: 2367-5519,1314-8338
DOI: 10.14748/vmf.v9i1.6454